Bertha Kalifon Madras

Bertha Kalifon Madras is a professor of psychobiology at Harvard Medical School. Her laboratory has focused on translational research, neurobiology of therapeutic and addictive substances, brain imaging, and medications development. Her laboratory discovered a class of compounds that are the most sensitive diagnostic imaging agents to detect Parkinson’s disease in living brain of patients. Using PET imaging, her research clarified drug mechanisms, abuse liability, and relationship between genotype and protein expression in living brain. Her current research focuses on the behavioral and molecular consequences of drugs introduced to adolescent primates, and whether these responses differ in adults. She is recipient of 19 U.S. and 27 international patents with collaborators. As an educator, she developed the first addictions course for HMS students and created the Cell Biology of Addiction Course at Cold Spring Harbor Laboratory. In public policy, she served as deputy director for demand reduction in the White House Office of National Drug Control Policy, a presidential appointment confirmed unanimously by the U.S. Senate. She is recipient of an NIH MERIT award, NIDA Public Service Award, American Academy of Addiction Psychiatry Founders’ Award, and other awards. The Better World Report (2006) cited her brain imaging invention as “one of 25 technology transfer (university to industry) innovations that changed the world.”

October 2024